Publications

  • ATPase copper transporting beta (ATP7B) is a novel target for improving the therapeutic efficacy of docetaxel by disulfiram/copper in human prostate cancer

    253

    Song, L., Nguyen, V., Xie, J., Jia, S., Chang, C. J., Uchio, E., & Zi, Xiaolin.

    Mol Cancer Ther. 2024, 23, 1-30.

  • Dysfunction in atox-1 and ceruloplasmin alters labile Cu levels and consequently Cu homeostasis in C. elegans

    252

    Weishaupt, A. K., Lamann, K., Tallarek, E., Pezacki, A. T., Matier, C. D., Schwerdtle, T., Aschner, M., Chang, C. J., Stürzenbaum, S. R., & Bornhorst, J.

    Front Mol Biosci. 2024, 11, 1-12.

  • One Carbon to Rule Them All: Formaldehyde is a One-Carbon Signal Connecting One-Carbon Metabolism and Epigenetic Methylation

    251

    Tenney, L., Pham, V. N., & Chang, C. J. 

    ACS Chem. Biol. 2024, 19, 1-4

  • A Transfer Hydrogenation Approach to Activity-Based Sensing of Formate in Living Cells

    250

    Crossley, S. W. M., Tenney, L., Pham, V. N., Xie, X., Zhao, M. W., & Chang, C. J. 

    J Am Chem Soc. 2024, 146, 1-12

  • Oxidative cyclization reagents reveal tryptophan cation–π interactions

    249

    Xie, X., Moon, P. J., Crossley, S. W. M., Bischoff, A. J., He, D., Li, G., Dao, N., Gonzalez-Valero, A., Reeves, A. G., McKenna, J. M., Elledge, S. K., Wells, J. A., Toste, F. D., & Chang, C. J.

    Nature. 2024, 627, 1-8

  • Formaldehyde regulates S-adenosylmethionine biosynthesis and one-carbon metabolism

    248

    Pham, V. N.; Bruemmer, K. J.; Toh, J. D.; Ge, E. J.; Tenney, L.; Ward, C. C.; Dingler, F. A.; Millington, C. L.; Garcia-Prieto, C. A.; Pulos-Homes, M. C.; Ingolia, N. T.; Bontel, L. B.; Esteller, M.; Patel, K. J.; Nomura, D. K.; Chang, C. J.

    Science 2023, 382, 1-10

    Related articles

    What is Epigenetics: Unveiling the Epigenetic Impact of Formaldehyde: A Hazardous Environmental Pollutant

    Berkeley News: Formaldehyde, a carcinogen, is also used by the body to regulate our genes.

  • In vivo bioluminescence imaging of labile iron in xenograft models and liver using FeAL-1, an iron-activatable form of D-luciferin

    247

    Gonziarz, R. L.; Jiang, H.; Tram, L.; Hugelshofer, C. L.; Ekpenyong, O.; Knemeyer, I.; Aron, A. T.; Chang, C. J.; Flygare, J. A.; Collisson, E. A.; Renslo, A. R.

    Cell Chem. Biol. 2023, 30, 1-10

  • Ciliary localization of a light-activated neuronal GPCR shapes behavior

    246

    Winans, A. M.; Friedmann, D.; Xiao, T.; Liu, Tsung-Li; Chang, C. J.; Isacoff, E. Y.

    Proc. Natl. Acad. Sci. U.S.A. 2023, 120, e2311131120

  • Porosity as a Design Element for Developing Catalytic Molecular Materials for Electrochemical and Photochemical Carbon Dioxide Reduction

    245

    De La Torre, P.; An, L.; Chang, C. J.

    Adv. Mater. 2023, 35, e2302122

  • Supramolecular Enhancement of Electrochemical Nitrate Reduction Catalyzed by Cobalt Porphyrin Organic Cages for Ammonia Electrosynthesis in Water

    244

    An, L.; Narouz, M. R.; Smith, P. T.; De La Torre, P.; Chang, C. J.

    Angew. Chem. Int. Ed. 2023, 62, e202305719

  • Capturing copper to inhibit inflammation

    243

    Chang, C. J.; Brady, D. C.

    Nature Chem. Biol. 2023, 19, 937-939

  • LOV thy neighbor: Mapping protein interactomes by genetically encodable photoproximity labeling

    LOV thy neighbor: Mapping protein interactomes by genetically encodable photoproximity labeling

    242

    Xie, X.; Jiang, Y.; Chang, C. J.

    Proc. Natl. Acad. Sci. U.S.A. 2023, 120, e2305211120

  • Interface of biomolecular condensates modulates redox reactions

    Interface of biomolecular condensates modulates redox reactions

    241

    Dai, Y.; Chamberlayne, C. F.; Messina, M. S.; Chang, C. J.; Zare, R. N.; You, L.; Chilkoti, A.

    Chem. 2023, 9, 1594-1609

  • Atp7b-dependent choroid plexus dysfunction causes transient copper deficit and metabolic changes in the developing mouse brain

    Atp7b-dependent choroid plexus dysfunction causes transient copper deficit and metabolic changes in the developing mouse brain

    240

    Washington-Hughes, C. L.; Roy, S.; Seneviratne, H. K.; Karuppagounder, S. S.; Morel, Y.; Jones, J. W.; Zak, A.; Xiao, T.; Boronina, T. N.; Cole, R. N.; Bumpus, N. N.; Chang, C. J; Dawson, T. M.; Lutsenko, S.

    PLoS Genet. 2023, 19, e1010558

  • Fluorescent Chemosensors textbook cover

    Fluorescent Chemosensors – Ch.3 -Activity-based Sensing: Principles and Probes for Selective Bioimaging

    239

    Editors – Wu, L.; Sedgwick, A. C.; He, X.-P.; James, T. D. | Chapter 3 Authors – Jia, S.; Chang, C. J.

    R. Soc. Chem. 2023, 17-39

  • Advanced Chemical Biology: Chemical Dissection and Reprogramming of Biological Systems textbook cover

    Metals in Chemical Biology in “Advanced Chemical Biology: Chemical Dissection and Reprogramming of Biological Systems”

    238

    Editors – Howard C. Hang, Matthew R. Pratt, Jennifer A. Prescher | Chapter Authors – Ge, E. J.; De La Torre, P.; Chang, C. J.

    Wiley-VCH 2023

  • Metalloallostery and Transition Metal Signalling: Bioinorganic Copper Chemistry Beyond Active Sites

    237

    Pham, V. N.; Chang, C. J.

    Angew. Chem. Int. Ed. 2023, 62, e202213644

  • Synergistic Porosity and Charge Effects in a Supramolecular Porphyrin Cage Promote Efficient Photocatalytic CO2 Reduction

    Synergistic Porosity and Charge Effects in a Supramolecular Porphyrin Cage Promote Efficient Photocatalytic CO2 Reduction

    236

    An, L.; De La Torre, P.; Smith, P. T.; Narouz, M. R.; Chang, C. J.

    Angew. Chem. Int. Ed. 2023, 62, e202209396

  • An Activity-Based Oxaziridine Platform for Identifying and Developing Covalent Ligands for Functional Allosteric Methionine Sites: Redox-Dependent Inhibition of Cyclin-Dependent Kinase 4

    An Activity-Based Oxaziridine Platform for Identifying and Developing Covalent Ligands for Functional Allosteric Methionine Sites: Redox-Dependent Inhibition of Cyclin-Dependent Kinase 4

    235

    Gonzalez-Valero, A.; Reeves, A. G.; Page, A. C. S.; Moon, P. J.; Miller, E.; Coulonval, K.; Crossley, S. W. M.; Xie, X.; He, D.; Musacchio, P. Z.; Christian, A. H.; McKenna, J. M.; Lewis, R. A.; Fang, E.; Dovala, D.; Yipin, L.; McGregor, L. M.; Schirle, M.; Tallarico, J. A.; Roger, P. P.; Toste, F. D., Chang, C. J.

    J. Am. Chem. Soc. 2022, 144, 22890-22901

  • Oxidation state-specific fluorescent copper sensors reveal oncogene-driven redox changes that regulate labile copper(II) pools

    Oxidation state-specific fluorescent copper sensors reveal oncogene-driven redox changes that regulate labile copper(II) pools

    234

    Pezacki, A. T.; Matier, C. D.; Gu, X.; Kummelstedt, E.; Bond, S. E.; Torrente, L; Jordan-Sciutto, K. L.; DeNicola, G. M.; Su, T. A.; Brady, D. C.; Chang, C. J.

    Proc. Natl. Acad. Sci. U.S.A. 2022, 119, e2202736119

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